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Product Details
Bulk supply high purity isonicotinaldehyde (4-pyridylmethylene)hydrazone 6957-22-8, Paid sample available
- Molecular Formula: C12H10 N4
- Molecular Weight: 210.238
- Vapor Pressure: 3.97E-05mmHg at 25°C
- Melting Point: 178 °C
- Boiling Point: 362.7°C at 760 mmHg
- PKA: 4.68±0.50(Predicted)
- Flash Point: 173.1°C
- PSA： 50.50000
- Density: 1.12g/cm3
- LogP: 1.92960
isonicotinaldehyde (4-pyridylmethylene)hydrazone(Cas 6957-22-8) Usage
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General Description |
Isonicotinaldehyde (4-pyridylmethylene)hydrazone is a chemical compound that is commonly used in medical and biochemical research. It is a hydrazone, a class of organic compounds derived from the reaction of ketones or aldehydes with hydrazine. isonicotinaldehyde (4-pyridylmethylene)hydrazone has been widely studied for its potential use as a chelating agent in the treatment of metal poisoning and as an anti-tumor agent. Additionally, it has been investigated for its antimicrobial properties and as a potential treatment for neurodegenerative diseases such as Alzheimer's. Isonicotinaldehyde (4-pyridylmethylene)hydrazone has also been used in the development of various coordination complexes and metallo-organic compounds with potential applications in catalysis and material science. |
InChI:InChI=1/C12H10N4/c1-5-13-6-2-11(1)9-15-16-10-12-3-7-14-8-4-12/h1-10H
6957-22-8 Relevant articles
Selective and reversible adsorption of cationic dyes by mixed ligand Zn(II) coordination polymers synthesized by reactant ratio modulation
Rachuri, Yadagiri,Subhagan, Sreevalsa,Parmar, Bhavesh,Bisht, Kamal Kumar,Suresh, Eringathodi
, p. 898 - 908 (2017)
Dye capture and separation through coord...
Co-crystals of tetrakis-1,2,3,4-(4′-carboxyphenyl)cyclobutane with dipyridyl spacers: Design and serendipity
Kole, Goutam Kumar,Tan, Geok Kheng,Koh, Lip Lin,Vittal, Jagadese J.
, p. 6190 - 6195,6 (2012)
Tetrakis-1,2,3,4-(4′-carboxyphenyl)cyclo...
A Water-Stable Twofold Interpenetrating Microporous MOF for Selective CO2 Adsorption and Separation
Pal, Arun,Chand, Santanu,Das, Madhab C.
, p. 13991 - 13997 (2017)
Self-assembly of bent dicarboxylate link...
Construction of one dimensional Co(II) and Zn(II) coordination polymers based on expanded N,N′-donor ligands
Zahedi, Mansoureh,Shaabani, Behrouz,Aygün, Muhittin,Kazak, Canan
, p. 461 - 468 (2018)
Four new 1-D coordination polymers [Zn(a...
Spontaneous resolution to absolute chiral induction: Pseudo-kagomé type homochiral Zn(II)/Co(II) coordination polymers with achiral precursors
Bisht, Kamal Kumar,Suresh, Eringathodi
, p. 15690 - 15693 (2013)
It is observed that conglomerate crystal...
Synthesis of Highly Stable Porous Metal-Iminodiacetic Acid Gels from A Novel IDA Compound
Chen, Wenjing,Jiang, Yanhong,Ding, Xuesong,Yan, Chaoguo,Han, Baohang
, p. 617 - 623 (2016)
In this work, a novel and simple flexibl...
A new pillared Cd-organic framework as adsorbent of organic dyes and as precursor of CdO nanoparticles
Ghomshehzadeh, Samira Gholamali,Nobakht, Valiollah,Pourreza, Nahid,Mercandelli, Pierluigi,Carlucci, Lucia
, (2020)
A new neutral cadmium-organic framework ...
A luminescent metal-organic framework with pre-designed functionalized ligands as an efficient fluorescence sensing for Fe3+ ions
Farahani, Yeganeh Davoudabadi,Safarifard, Vahid
, p. 428 - 435 (2019)
Metal-organic frameworks are a class of ...
Construction of five dicyanamide based coordination polymers with diverse dimensionality: Synthesis, characterization and photoluminescence study
Das, Anamika,Bhattacharya, Biswajit,Maity, Dilip Kumar,Halder, Arijit,Ghoshal, Debajyoti
, p. 585 - 591 (2016)
A family of dicyanamide bridged compound...
Ruthenium(ii)-catalysed 1,2-selective hydroboration of aldazines
Gunanathan, Chidambaram,Pradhan, Subham,Thiyagarajan, Subramanian
supporting information, p. 7147 - 7151 (2021/08/30)
Herein, an efficient and simple catalyti...
Design, synthesis and biological evaluation of Schiff’s base derivatives as multifunctional agents for the treatment of Alzheimer’s disease
Shi, Jian,Zhou, Yi,Wang, Keren,Ma, Qinge,Wei, Rongrui,Li, Qingfeng,Zhao, Yiyang,Qiao, Zhanpin,Liu, Shuang,Leng, Yumin,Liu, Wenmin,Sang, Zhipei
, p. 624 - 634 (2020/11/30)
A series of Schiff’s base derivatives wa...
6957-22-8 Process route
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-
872-85-5
pyridine-4-carbaldehyde
-
-
6957-22-8
4-pyridinealdazine
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
ethanol;
at 20 ℃;
for 0.333333h;
|
92%
|
|
With
hydrazine hydrate;
In
methanol;
for 3h;
Reflux;
|
90%
|
|
With
hydrazine hydrate;
In
ethanol;
for 24h;
Inert atmosphere;
|
90%
|
|
With
hydrazine hydrate;
In
ethanol;
at 20 ℃;
for 24h;
Inert atmosphere;
|
87%
|
|
With
formic acid; hydrazine hydrate;
In
ethanol;
at 20 ℃;
for 24h;
|
86%
|
|
With
formic acid; hydrazine;
In
ethanol; water;
at 20 ℃;
for 1h;
|
86%
|
|
With
formic acid; hydrazine;
In
ethanol; water;
at 20 ℃;
for 24h;
|
86%
|
|
With
formic acid; hydrazine;
In
ethanol;
at 20 ℃;
for 24h;
|
79%
|
|
With
formic acid; hydrazine;
In
ethanol;
at 20 ℃;
for 24h;
|
79%
|
|
With
phthaloyldihydrazine;
In
ethanol;
for 1h;
Heating;
|
|
|
With
hydrazine hydrate;
|
|
|
With
hydrazine hydrate;
|
|
|
With
sodium hydroxide; hydrazinium sulfate;
In
water;
for 2h;
|
0.7%
|
|
With
acetic acid; hydrazine;
In
ethanol;
Reflux;
|
|
|
With
hydrazine hydrate;
In
ethanol;
Reflux;
|
-
-
pyridine-4-ylmethylenehydrazine
-
-
6957-22-8
4-pyridinealdazine
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
ethanol;
|
70%
|
6957-22-8 Upstream products
-
872-85-5
pyridine-4-carbaldehyde
-
51832-68-9
Pyridine-4-carboxaldehyde hydrazone
-
18708-54-8
N′-(pyridin-4-yl-benzylidene)-4-methylbenzenesulfonohydrazide
-
83710-34-3
N'-[1-Pyridin-4-yl-meth-(E)-ylidene]-hydrazinecarboxylic acid ethyl ester
isonicotinaldehyde (4-pyridylmethylene)hydrazone
CAS:6957-22-8
Purity:99%
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